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bismuth sulfate is an inorganic compound with the formula Ba(Sm)(SO)(CH3). It is a white crystal that decomposes with water or alc into a basic salt and is soluble in acids. It is used to treat diarrhea, especially traveler’s diarrhea, and to prevent infections caused by parasites such as giardia and cryptosporidiosis in people who are traveling to countries where these diseases are common. It also is used to relieve symptoms of upset stomach, such as heartburn, indigestion, and nausea, in adults and teenagers. It is available without prescription.

The drug binds to sulfate-reducing bacteria (SRB) in the intestinal tract, which causes them to produce hydrogen sulfide and slows intestinal transit time. It may also inhibit the secretion of Clostridium difficile toxins. In addition, it has antisecretory and gastrointestinal antiinflammatory activities. Bismuth subsalicylate is a commonly used medication in the treatment and prevention of travelers’ diarrhea.

Before taking bismuth subsalicylate, tell your doctor and pharmacist if you are allergic to it or to other salicylate pain relievers (aspirin, choline magnesium trisalicylate, acetylsalicylic acid, diflunisal, salsalate) or to other medications (such as antacids, iron, vitamins, and cholestyramine). Your doctor and pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dose of any drug without your doctor’s approval.