Photothermal therapy of Fe3O4 magnetic nanoparticles and their custom synthesized composite materials

Fe3O4 The nanoparticles used in biomedicine are characterized by their high magnetic saturation and biocompatibility. Recently, Fe3O4 Nanoparticles attracted researchers’ attention as a type of new photothermal reagent.Fe3O4 (microspheres) clusters, compared to Fe3O4 with the same crystallization, have a superior photothermal effect. This is due in part to their stronger absorption functions within the near-infrared spectrum. Fe3O4 Microspheres also showed a greater photothermal treatment under near-infrared lights.
The photothermal properties can be further explored by utilizing Fe3O4 Researchers have found that with increasing storage time, Fe3O4 is partially oxidized to Fe2O3. They also discovered that polymer ligands are more protective than small molecule ligands. Fe3O4 becomes partially oxidized with the increase in storage time. Research has shown that polymer molecules have a greater protective effect than small molecule ones, and also have a strong anti-oxidation capability.

By oxidative self polymerization of PDA, we have created a composite microsphere with a core and shell structure that is biocompatible. The composite microspheres exhibit greater photothermal effects and absorption near infrared compared to Fe3O4 microspheres. The photothermal and near-infrared effects of Fe3O4&PDA Composite Microspheres are both enhanced with increasing thickness of PDA shell.
The nanoparticles will enter the bloodstream in the body and combine quickly with different proteins to create a protein crown. This is then absorbed and eliminated by autoimmune system and mononuclear lymphocytes. Biomimetic technology was used to create the Fe3O4 Microspheres coated with RBC membranes improve the long circulation of Fe3O4 in the body. They also enhance the effect of photothermal therapy on the animal.
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Nano-Ferrosoferric oxide Fe3O4 have a special application in biomedicine

What is nano Ferrosoferric oxid? Iron (II and III) Oxide is also known by the name Fe3O4. Black Fe3O4 is an oxide of mixed valence of iron. It has a melting point 1597, and a mass density of 5,18g/cm3. It is not soluble but soluble when mixed with acid. It is found in nature as magnetite, with a strong sub-magnetite. At room temperature it has a high conductivity.
Ferromagnetic or ferromagnetic substances undergo a second-order transition into paramagnetic compounds above the Curie temperature. Fe3O4’s Curie Temperature is 585.
The powder of nano-ferrosoferric (Fe3O4) oxide is magnetic and moves in a directional manner when exposed to an external magnetic field. In certain ranges, its particle size is superparamagnetic. It can also generate heat under the influence of an external alternating magnetic field. It is widely used because its chemical properties are stable.
What are magnetic Nanoparticles?
Magnetic Nanoparticles/Magnetic Nanoparticles (MNPs) are new materials with rapid development and high application value in recent years. The application of magnetic nanoparticles has increased in recent years.
The nano-Ferrosoferric-oxide Fe3O4 exhibits special magnetic properties when reduced to a nanometer-scale. These magnetic properties are not found in bulk materials because of the small-size effect, surface-effect, quantum-size effect and macroscopic-quantum tunneling effect. This makes it a very useful material in industries, biomedicine and other fields.
In biomedicine, nano-Ferrosoferricoxide Fe3O4 has many applications.

Magnetic polymer nanospheres, also known as immune magnet microspheres, is composed of magnetic particles and polymer scaffolds for the preparation of biomedical material. The polymer materials used include starch (dextrin), dextrin polyacrylic, silane, polyethylene polystyrene polyacrylic, gelatin albumin ethylcellulose.
Fe3O4 has stable properties and is non-toxic. It can be used for magnetic separations, tumor heat treatment, cell markers, contrast research and retinal detachment surgeries. The magnetic hyperthermia treatment is a hotspot for domestic research, particularly in the treatment and prevention of cancer-related drug carriers.
Fe3O4 ferroferric oxide supplier
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